Description
This document on pharma management discusses uses and contradictions of DHEA.
DHEA 25mg 60 Capsules USES
Dehydroepiandrosterone (DHEA) is a steroid hormone that's produced by the adrenal glands. The body converts DHEA to male and female sex hormones, such as estrogen and testosterone. DHEA levels typically peak by the time people are in their 20s and decline with age, which is why there has been considerable interest in DHEA and its role in aging. In fact, DHEA supplements have been touted as an anti-aging hormone because lower levels of DHEA have been reported in some people with type 2 diabetes, breast cancer, heart disease, osteoporosis, AIDS, adrenal insufficiency, kidney disease and anorexia. Certain medications may also deplete DHEA, such as corticosteroids, insulin, opiates and danazol. DHEA is used as an "anti-aging" hormone and for conditions in which DHEA levels have been found to be low, however, there are very few large, well-designed human studies showing that it's effective.
The gradual decline in the body's DHEA levels correlate with loss of muscle mass, decreased bone density, and a decline in immune function In animal studies, DHEA has shown some promise in reducing genetic or dietinduced obesity. A study funded by the National Institutes of Health looked at the effect of DHEA (50 mg a day) compared to a placebo for weight loss in 56 overweight adults between the ages of 65 and 78. At the end of the six month study, people taking DHEA lost an average of two pounds compared to the people taking the placebo, who gained just over one pound. Although overall weight loss was minimal, results were more promising when fat loss around the abdomen was assessed. After six months, women taking DHEA lost 10% of their abdominal fat and men lost 7%. A large study involving 942 men in the Massachusetts Male Aging Study looked at men between the ages of 40 and 70, first in 1987 to 1989 and then again in 1995 to 1997. Researchers found that fat around the abdomen (called central obesity) was associated with lower DHEA levels. CONTRAINDICATIONS DHEA is contraindicated in patients with benign prostatic hyperplasia, estrogen-responsive tumors (such as those of the breast and uterus), or prostate cancer because of DHEA's potential for promoting growth of these tumors. Avoid using DHEA in pregnant or breast-feeding patients 23 ( 3 )
doc_768371006.doc
This document on pharma management discusses uses and contradictions of DHEA.
DHEA 25mg 60 Capsules USES
Dehydroepiandrosterone (DHEA) is a steroid hormone that's produced by the adrenal glands. The body converts DHEA to male and female sex hormones, such as estrogen and testosterone. DHEA levels typically peak by the time people are in their 20s and decline with age, which is why there has been considerable interest in DHEA and its role in aging. In fact, DHEA supplements have been touted as an anti-aging hormone because lower levels of DHEA have been reported in some people with type 2 diabetes, breast cancer, heart disease, osteoporosis, AIDS, adrenal insufficiency, kidney disease and anorexia. Certain medications may also deplete DHEA, such as corticosteroids, insulin, opiates and danazol. DHEA is used as an "anti-aging" hormone and for conditions in which DHEA levels have been found to be low, however, there are very few large, well-designed human studies showing that it's effective.
The gradual decline in the body's DHEA levels correlate with loss of muscle mass, decreased bone density, and a decline in immune function In animal studies, DHEA has shown some promise in reducing genetic or dietinduced obesity. A study funded by the National Institutes of Health looked at the effect of DHEA (50 mg a day) compared to a placebo for weight loss in 56 overweight adults between the ages of 65 and 78. At the end of the six month study, people taking DHEA lost an average of two pounds compared to the people taking the placebo, who gained just over one pound. Although overall weight loss was minimal, results were more promising when fat loss around the abdomen was assessed. After six months, women taking DHEA lost 10% of their abdominal fat and men lost 7%. A large study involving 942 men in the Massachusetts Male Aging Study looked at men between the ages of 40 and 70, first in 1987 to 1989 and then again in 1995 to 1997. Researchers found that fat around the abdomen (called central obesity) was associated with lower DHEA levels. CONTRAINDICATIONS DHEA is contraindicated in patients with benign prostatic hyperplasia, estrogen-responsive tumors (such as those of the breast and uterus), or prostate cancer because of DHEA's potential for promoting growth of these tumors. Avoid using DHEA in pregnant or breast-feeding patients 23 ( 3 )
doc_768371006.doc